Ott
                        In the absence of                            1..am acknowledging with
                 interest and      appreciation            ipt,ot 7our      letter and  etiolosures
                 19  JunR 1953,*,,rvferl@nce DU          733@@l2.@172,   (MI)    and iiiias     2-61-3ui-i
                        In this acknowledf,-
                                                 Aunt     ve desire   to   point   out   in    a    prelirdnai-,f
                 way  t,hat  Initial    offortp eitlior have         been   Lmdej   or   are    under    ccnb:ld-
                 eration in this       ootuitry2.along      the to3.lowing,]4necl3
                             1.@   Collection-of orgot               the,preparation       of  L-JD as   Well."
                 as air otlier derivptivee        of'lyseriic acid for continued                toot.Ln  of
                                                                                                               4@@'
                 2                                                                          -ents  by     use of
                             2,   Screening      of other potential         carebrnl     a@,
                 special tests nrul irkthodoj         lnc3.udine,    the  use   of   oticel;   ogra   1113
  41t.                             ':@tu                   -,id,   et;peciauy   iitus2lirouatc,    produe4ng,
                             @l        -vey of   Amgi      a
                 potent cerabral agents; e.g, Clitocybe subilliwens, certain ru3tq,,
                 used    to     aluy fe&r-     A.n,S&telUto     countriosi,     pobalblv      Uh$mA.
                                   Surver of ferns.,: de yet -unidentified)"' prodticitit             thi@ougli
                 their   spores,, mental disturbances and even death (in Aknimals).
                                   Survey   o.C   14.unsian    and    other    literature    dea.Ung    with
                 fimt@i  u.-;ed Jn imdicin2f.,, in ceremoiiias and an into2icart, s  n  coti
                                                                                                    ar      as
                 or otherwise, exnopting food
                                   Survey   tuid   develoi-inent    of    ,lonsible    antidotes    and    other
                 prevontive reasures against offects of cerebral a&ents
       2                            Ilp-to-date extenrive bibllographles on
                                   a.   l,yeergic acid and derivatives
                                   b,   (,Vier alents of p.,iyahocliemic.-a lntereat
                                   c,@  Anoxia     and     compomds     Aau4ing.,mental     dicorders   5  lyl
                        In  responiia,to     your,question      concoming       anybody       doing    work in

             Llie @,nLLe(i -States 9.itrilar Lo 5,our,s, i nt:kliry In n w I.,t@ini7
                                                                             rirle to ob-
             taiii r%LrLher in.Cariratlin regp@mU.np, t.@uch work it,.,i(ier wa@,@ or plamied2.
                   @l coupcrative imdartakintt betvm-n our two couiitrifo.,; tay be
                 f ltable such as ie; now in-   O&ms
             pro                                      9 in the study or Soviot. research.,-'@
                                              Pr
             on cholj-nesterase2.  If you   consider -such co.Ilaboratiun desirable.,   we
              il-1 bp rleaved to have your    comaents and ougtentions for cou&bo
             ti,)n in a progrzo of studve
                                                    Cordially  yoiiz,v@
                                                          lfig losistant    rector
              2                                         Act
                                    4' '@3
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