Why would anyone want create novel virus capable causing pandemic ? Ever since virologists gained tools manipulating virus ’ genes , argued could get ahead potential pandemic exploring close given animal virus might making jump humans.And justified lab experiments enhancing ability dangerous animal viruses infect people , virologists asserted.With rationale , recreated 1918 flu virus , shown almost extinct polio virus synthesized published DNA sequence , introduced smallpox gene related virus.These enhancements viral capabilities known blandly gain-of-function experiments.With coronaviruses , particular interest spike proteins , jut around spherical surface virus pretty much determine species animal target.In 2000 Dutch researchers , instance , earned gratitude rodents everywhere genetically engineering spike protein mouse coronavirus would attack cats .