Her plan take genes coded spike proteins possessing variety measured affinities human cells , ranging high low.She would insert spike genes one one backbone number viral genomes ( “ reverse genetics ” “ infectious clone technology ” ) , creating series chimeric viruses.These chimeric viruses would tested ability attack human cell cultures ( “ vitro ” ) humanized mice ( “ vivo ” ) .And information would help predict likelihood “ spillover , ” jump coronavirus bats people.The methodical approach designed find best combination coronavirus backbone spike protein infecting human cells.The approach could generated SARS2-like viruses , indeed may created SARS2 virus right combination virus backbone spike protein.It yet stated Shi generate SARS2 lab records sealed , seems certainly right track done .